Yes. Simple Setup. The USB Hub with the device drivers creates a separate Virtual COM port for each USB at the required speed. OpenCPN then acts as the Multiplexer when you make separate Connections for each of the virtual COM ports created. Example:

Inateck USB3.0 3-port hub with gigabit ethernet port $20

Bu-353-S4 GPS puck $25

dAISy AIS Receiver $70

Tiny Seatalk Link $150 for Raymarine Instruments (up to ST60).

Label the ports for the devices and use those ports or you'll be redoing OpenCPN “Connections”.

Install each device's drivers.

or another example, Vesper AIS and RS422 NEMA instruments.

For more about Supplementary Hardware or consult with a marine electronics service.

A multiplexer will join multiple sources into a single output to OpenCPN. Multiplexers come in a great variety, to do many different jobs, read the specs.

Simply fill in the virtual port name manually, the field is not limited to selection of the ports that were detected.

You can add absolutely anything to the filter (Click on the “Add” button), the predefined list is there just to save you some typing for the most common message types.